Uncategorized

Does stress make us less able to forget?

If you ever blacked out during an exam or lost forgot your lines when speaking in front of an audience, the notion that stress makes us unable to forget appears counterintuitive. But what if we actually try to forget something through active suppression? In that case, it appears that stress is actually preventing us to… Continue reading Does stress make us less able to forget?

NP&PP department, Older adults, Review, SSRI

The effects of selective serotonin reuptake inhibitors on memory functioning in older adults: A systematic literature review

SSRIs are still widely prescribed to treat various psychiatric indications even in older adults. The side effects of SSRIs have been characterized in younger adults, but this is not the case for older adults. One concern is that SSRI treatment may contribute to a deterioration of cognitive performance in this older patient population. This systematic… Continue reading The effects of selective serotonin reuptake inhibitors on memory functioning in older adults: A systematic literature review

cognition enhancement, publication

Acute treatment with the PDE4 inhibitor roflumilast improves verbal word memory in healthy old individuals: a double-blind placebo-controlled study

After many years of animal research, in which we found that inhibition of the enzyme phosphodiesterase type 4 (PDE4) improved memory in animals, we now find first evidence that this mechanism also works in humans. In this study, we tested how many words older participants (aged between 60 and 85 years old) could remember from… Continue reading Acute treatment with the PDE4 inhibitor roflumilast improves verbal word memory in healthy old individuals: a double-blind placebo-controlled study