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Metabolomics and integrated network analysis reveal roles of endocannabinoids and large neutral amino acid balance in the ayahuasca experience

What is the metabolomic fingerprint of the ayahuasca experience? In a recent study, we collected plasma samples from 23 volunteers both before and during the ayahuasca experience. Samples were screened for concentrations of 164 targeted biomarkers, including endocannabinoids, markers of amino acid metabolism, steroids, ceramindes, etc. What did this fingerprint look like? Changes in serotonin… Continue reading Metabolomics and integrated network analysis reveal roles of endocannabinoids and large neutral amino acid balance in the ayahuasca experience

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Persisting Effects of Ayahuasca on Empathy, Creative Thinking, Decentering, Personality, and Well-Being

A new study from our group: Collaboration with facilitators of ayahuasca ceremonies throughout the Netherlands has allowed us to assess if Ayahuasca, a psychedelic brew of Amazonian origin, induces persisting short- and long-term effects on emotional and cognitive functioning of healthy volunteers. It was found that 24 hours after participating in an ayahuasca ceremony, participants… Continue reading Persisting Effects of Ayahuasca on Empathy, Creative Thinking, Decentering, Personality, and Well-Being