Memory, Older adults, Review

Scopolamine vs biperiden as cognitive deficit models: from animal to human research

In a recent review paper by professor Arjan Blokland, the effects of scopolamine and biperiden (and pirenzepine) are compared in animal studies and related to findings in humans. Scopolamine is used as a golden standard to induce memory impairments in animals and man. It has been used to validate new drugs for dementia-related disorders. However,… Continue reading Scopolamine vs biperiden as cognitive deficit models: from animal to human research

Cannabis, NPS

A comparison of acute neurocognitive and psychotomimetic effects of a synthetic cannabinoid and natural cannabis at psychotropic dose equivalence

Since about 20 years, smoking mixtures, such as Spice or K2, have become popular alternatives for cannabis. These smoking mixtures contain synthetic cannabinoids, which are reported to cause more psychological problems and stronger behavioral impairment. However, comparing the effects of synthetic cannabinoids with natural cannabis has been problematic due to the differences in pharmacological properties… Continue reading A comparison of acute neurocognitive and psychotomimetic effects of a synthetic cannabinoid and natural cannabis at psychotropic dose equivalence

Psychedelic-Assisted Psychotherapy

Psychedelic-Assisted Psychotherapy—A Systematic Review of Associated Psychological Interventions

What do we mean when we say Psychedelic-Assisted Psychotherapy (PAP)? While some general guidelines to conduct PAP treatment programs are quite established and agreed upon, the degree of variability within the preparation - drug session - integration model is still very high. Our latest publication collects, compares and analyses the different therapeutic approaches that are… Continue reading Psychedelic-Assisted Psychotherapy—A Systematic Review of Associated Psychological Interventions