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Multifaceted Research with Psychedelics @ Maastricht University

We conduct a large variety of studies, all aimed at better understanding psychedelic mechanisms of action, and their clinical applications. To get a glimpse at some of the different aspects of our research, check out the video from our recent symposium, where our PhD candidates share some of the work going on at our department.… Continue reading Multifaceted Research with Psychedelics @ Maastricht University

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Cortisol reactivity impairs suppression-induced forgetting.

Suppressing thoughts of an unwanted memory can lead us to forget about it. This can be beneficial for our mental health by allowing us to let go of negative memories and avoid revisiting certain events that we would rather not think about. Stress related disorders, such as post-traumatic stress disorder (PTSD), can cause an impairment… Continue reading Cortisol reactivity impairs suppression-induced forgetting.

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Dopaminergic and noradrenergic modulation of stress-induced alterations in brain activation associated with goal-directed behaviour

Getting a glass of water when you’re thirsty or having a snack when you’re hungry is called goal-directed behaviour. However, when you repeat that behaviour many times the sight of water or a snack may be sufficient to eat and drink. Behaviour is then no longer driven by the goal to alleviate the hunger and/or… Continue reading Dopaminergic and noradrenergic modulation of stress-induced alterations in brain activation associated with goal-directed behaviour

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Healthy males and females who want to participate in a placebo-controlled study on physiological and cognitive effects of Kratom (mitragynine).

Kratom is a plant, native of Eastern countries, that is popular as a novel psychoactive substance (NPS). Its main compound is mitragynine (MG). The purpose of this study is to asses the physiological and cognitive effects of mitragynine in healthy subjects (phase 1 study). The study consists of 4 test days of ± 7.5 hours… Continue reading Healthy males and females who want to participate in a placebo-controlled study on physiological and cognitive effects of Kratom (mitragynine).

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Effect of Cannabidiol (CBD) and Δ9-Tetrahydrocannabinol (THC) on Driving Performance

A recent study from our group in collaboration with the Lambert Initiative at Sydney University shows that THC-dominant cannabis can cause impairment of on-road driving and cognitive function for up to 4 hours after vaporization. Cannabis that contained CBD only did not affect driving and cognition. Cannabis that contained both THC and CBD produced impairment… Continue reading Effect of Cannabidiol (CBD) and Δ9-Tetrahydrocannabinol (THC) on Driving Performance